| May 2006 · Vol. 18, No. 5 EXAMINING THE EVIDENCE
CLINICAL IMPLICATIONS OF KEY TRIALS
Q How common is hypoactive sexual desire disorder?
Leiblum SR, Koochaki PE, Rodenberg CA, Barton IP, Rosen RC. Hypoactive sexual desire disorder in postmenopausal women: US results from the Women’s International Study of Health and Sexuality (WISHeS). Menopause. 2006;13:46–56.
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Fast Track
Diminished health, both physical and mental, was linked to hypoactive sexual desire disorder
Testosterone, by any route, positively affects sexual function after spontaneous or surgical menopause
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JoAnn
V.
Pinkerton,
MDProfessor of Obstetrics and Gynecology, Director of Women’s Midlife Health, University of Virginia, Charlottesville. Dr. Pinkerton is a member of the OBG Management Board of Editors.
A This disorder is prevalent in women at all reproductive stages. Younger, surgically postmenopausal women were at greatest risk among 4 demographic groups analyzed (TABLE). Prevalence ranged from 26% in surgically postmenopausal women aged 20 to 49, to 9% in naturally postmenopausal women.
Hypoactive sexual desire disorder (HSDD) should be recognized as an important quality-of-life issue, particularly for those at increased risk, this report concluded. WISHeS is the first study to report the prevalence of HSDD in US women using well-validated questionnaires, and to assess sexual, relationship, and quality-of-life correlates. Psychosocial distress and significant decrements in general health status, including aspects of mental and physical health, were linked to HSDD.
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