August 2006 · Vol. 18, No. 8Drug therapy for incontinence: New agents, new applications
Profiles and practice recommendations for 3 new drugs for urinary incontinence, plus new potential for an “old” medication
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Fast Track
Both oxybutynin and tolterodine reduced urge incontinence, but oxybutynin also reduced urinary frequency
Darifenacin increased mean, minimum, and median “warning times,” the interval from first urge to urination
In light of the strong placebo effect, start with behavorial therapy for overactive bladder
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L.
Lewis
Wall,
MDProfessor of Obstetrics and Gynecology and Director, Division of Urogynecology and Reconstructive Pelvic Surgery, Washington University School of Medicine, St. Louis, Mo
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